Fibrinolytic and Proteolytic Enzymes, Medical Use by Jeffrey Dach MD

 
Fibrinolytic and Proteolytic Enzymes, Medical Use by Jeffrey Dach MD

Sam is a 24 year old with a swollen painful ankle after an injury playing basketball.  Xrays are negative for fracture, but Sam cannot walk and stays at home applying ice packs.  Jim is a 62 year old who sees a Cardiologist for episodes of chest pain, and was diagnosed with “stable angina” and given nitro pills.  Ralph sees a urologist for an enlarged prostate, and was given the diagnosis of BPH (Benign Prostatic Hyperplasia).  Sue has chronic sinusitis and bronchitis with thick mucus.   Neal had two episodes of a “mild” stroke with transient slurred speech.  Left Image sprained ankle courtesy of wikimedia commons.

What do all these patients have in common?

They could all benefit from proteolytic enzymes available at the health food store without a prescription.  Since these are supplements, it is unlikely their doctor would mention it.

The three major enzymes are
1) Serrapeptidase,
2) Nattokinase and
3) Lumbrokinase.

Serrapeptidase is made by the silk worm, and used to digest the cocoon.  Serrapeptidase has anti-inflammatory activity, and has been suggested as a replacement for NSAID anti-inflammatory drugs like Ibuprofen and Indomethacin.   Serrapeptidase is just as effective without the adverse side effects of NSAIDS.

“Serratiopeptidase or serrapeptase is a protein (proteolytic) enzyme isolated from the non-pathogenic enterobacteria Serratia E15 found in silkworms. Serratiopeptidase often prescribed in various specialties like surgery, orthopedics, otorhinolaryngology, gynecology and dentistry for its anti-inflammatory, anti-endemic and analgesic effects . In the research in recent years, exploration illustrated enzyme also plays a vital role in the management of atherosclerosis as it does possess fibrinolytic and caseinolytic properties. ” quote (1)

Blood clots, cysts and arterial plaque are all gradually dissolved. Over 50 clinical trials from Europe and Asia attest to the ability of Serrapeptase to successfully treat conditions ranging from sprains, torn ligaments, post-operative swelling (edema), fibrocystic breast disease, deep vein thrombosis (DVT), carpal tunnel syndrome, ear, nose and throat infections and atherosclerosis. Serrapeptase literally digests inflammatory tissue.”Quote(8)

Serrapeptidase useful for Ankle Sprains

Dr Esch studied ankle sprains in 66 patients finding the use of Serrapeptidase significantly reduced pain and swelling after the injury.(2)

Nattokinase

Nattokinase comes from fermented soy products and a staple of the Japanese diet.  Nattokinase has fibrinolytic effects and thought to be useful in prevention of cardiovascular disease, and is currently undergoing a clinical trial at University of Southern California, Dr Howard Hodis. (70):

“Various animal and human trials have demonstrated that NK improves blood circulation and helps decrease the risk of a variety of cardiovascular diseases without producing any adverse side effects.”quote (22)

 

Lumbrokinase

Lumbrokinase comes from earthworms and is the most potent fibrinolytic enzyme of the three.  It was found effective in improving myocardial perfusion and reducing angina symptoms in patients with coronary artery disease.(1)

Left Image: Improvement in Myocardial Perfusion Scan in Angina Patient after Lumbrokinase. Courtesy of  Kasim 2009. Left column before treatment. Right column alter treatment.  Note perfusion defect between white arrows resolves after treatment.(26)

Lumbrokinase was useful in treatment of  Ischemic Stroke, angina, myocardial ischemia,  deep venous thrombosis, hypertension,  vascular dementia  and hypercoagulation-associated complications.(27)

“serrapeptase is not considered a strong fibrinolytic enzyme and should primarily be used for inflammation and pain association with oral/facial surgeries, sinus infection, arthritis, or chronic airway diseases. Respectively, nattokinase and lumbrokinase would be more suited for patients with mild and severe hypercoagulation or for patients with low and high cardiovascular risks.” Quote from (27)

 
Proteolytic Enzymes Dissolve Biofilms – Assist Antibiotics


A number of studies show that proteolytic enzymes enhance antibiotic effects by breaking up biofilms.  The enzymes are useful add-ons for antibiotic treatment of infectious micro-organisms known to produce bio-films.  Left image Scanning Electron Microscope of BioFilm fibrin strands courtesy of CNN.

Find Lumbrokinase, Nattokinase and Serrapeptidase on Amazon

Jeffrey Dach MD
7450 Griffin Road, Suite 180/190
Davie, Fl 33314
954-792-4663

Links and References

see original article:  https://jeffreydachmd.com/2018/06/fibrinolytic-proteolytic-enzymes-medical-use/